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Mechanisms of deadenylation-dependent decay

Degradation of mRNAs plays an essential role in modulation of gene expression and in quality control of mRNA biogenesis. Nearly all major mRNA decay pathways characterized thus far in eukaryotes are initiated by deadenylation, i.e., shortening of the mRNA 3′ poly(A) tail. Deadenylation is often a ra...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chen, Chyi-Ying A., Shyu, Ann-Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624885/
https://ncbi.nlm.nih.gov/pubmed/21957004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.40
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