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Mechanisms of deadenylation-dependent decay

Degradation of mRNAs plays an essential role in modulation of gene expression and in quality control of mRNA biogenesis. Nearly all major mRNA decay pathways characterized thus far in eukaryotes are initiated by deadenylation, i.e., shortening of the mRNA 3′ poly(A) tail. Deadenylation is often a ra...

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Autori principali: Chen, Chyi-Ying A., Shyu, Ann-Bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624885/
https://ncbi.nlm.nih.gov/pubmed/21957004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.40
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