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Mechanisms of deadenylation-dependent decay

Degradation of mRNAs plays an essential role in modulation of gene expression and in quality control of mRNA biogenesis. Nearly all major mRNA decay pathways characterized thus far in eukaryotes are initiated by deadenylation, i.e., shortening of the mRNA 3′ poly(A) tail. Deadenylation is often a ra...

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書目詳細資料
Main Authors: Chen, Chyi-Ying A., Shyu, Ann-Bin
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624885/
https://ncbi.nlm.nih.gov/pubmed/21957004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.40
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