Structural origins of the exonuclease resistance of a zwitterionic RNA

Nuclease resistance and RNA affinity are key criteria in the search for optimal antisense nucleic acid modifications, but the origins of the various levels of resistance to nuclease degradation conferred by chemical modification of DNA and RNA are currently not understood. The 2′-O-aminopropyl (AP)-...

詳細記述

書誌詳細

出版年:	Proc Natl Acad Sci U S A
主要な著者:	Teplova, Marianna, Wallace, Scot T., Tereshko, Valentina, Minasov, George, Symons, Alice M., Cook, P. Dan, Manoharan, Muthiah, Egli, Martin
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 1999
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24421/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14240
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