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Structural origins of the exonuclease resistance of a zwitterionic RNA

Nuclease resistance and RNA affinity are key criteria in the search for optimal antisense nucleic acid modifications, but the origins of the various levels of resistance to nuclease degradation conferred by chemical modification of DNA and RNA are currently not understood. The 2′-O-aminopropyl (AP)-...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Teplova, Marianna, Wallace, Scot T., Tereshko, Valentina, Minasov, George, Symons, Alice M., Cook, P. Dan, Manoharan, Muthiah, Egli, Martin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588690/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14240
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