Structural origins of the exonuclease resistance of a zwitterionic RNA
Nuclease resistance and RNA affinity are key criteria in the search for optimal antisense nucleic acid modifications, but the origins of the various levels of resistance to nuclease degradation conferred by chemical modification of DNA and RNA are currently not understood. The 2′-O-aminopropyl (AP)-...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24421/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14240 |
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