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Catalytic and structural role of the metal ion in dUTP pyrophosphatase

The metal ion dependence of the catalytic activity of recombinant Escherichia coli dUTP pyrophosphatase (dUTPase), an essential enzyme preventing incorporation of uracil into DNA, has been investigated by steady-state kinetic, electron paramagnetic resonance, and electron nuclear double resonance me...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Mustafi, Devkumar, Bekesi, Angela, Vertessy, Beata G., Makinen, Marvin W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12721364/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1031504100
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