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Catalytic and structural role of the metal ion in dUTP pyrophosphatase

The metal ion dependence of the catalytic activity of recombinant Escherichia coli dUTP pyrophosphatase (dUTPase), an essential enzyme preventing incorporation of uracil into DNA, has been investigated by steady-state kinetic, electron paramagnetic resonance, and electron nuclear double resonance me...

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Detalhes bibliográficos
Main Authors: Mustafi, Devkumar, Bekesi, Angela, Vertessy, Beata G., Makinen, Marvin W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156259/
https://ncbi.nlm.nih.gov/pubmed/12721364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031504100
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