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Cleavage of Type II Collagen by Cathepsin K in Human Osteoarthritic Cartilage
Cathepsin K is a cysteine protease of the papain family that cleaves triple-helical type II collagen, the major structural component of the extracellular matrix of articular cartilage. In osteoarthritis (OA), the anabolic/catabolic balance of articular cartilage is disrupted with the excessive cleav...
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Main Authors: | , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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American Society for Investigative Pathology
2008
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2438294/ https://ncbi.nlm.nih.gov/pubmed/18511517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070494 |
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