Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
Analysis of perforin-deficient mice has identified the cytolytic pathway and perforin as the preeminent effector molecule in T cell-mediated control of virus infections. In this paper, we show that mice lacking both granzyme A (gzmA) and granzyme B (gzmB), which are, beside perforin, key constituent...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1999
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24171/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10570179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.24.13950 |
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