Concerted Action of the FasL/Fas and Perforin/Granzyme A and B Pathways Is Mandatory for the Development of Early Viral Hepatitis but Not for Recovery from Viral Infection

Cytotoxic T lymphocytes (CTL) play a major role in the recovery from primary viral infections and the accompanying tissue injuries. However, it is unclear to what extent the two main cytolytic pathways, perforin-granzyme A and B exocytosis and Fas ligand (FasL)-Fas interaction, contribute to these p...

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Main Authors: Balkow, Sandra, Kersten, Astrid, Tran, Thi Thanh Thao, Stehle, Thomas, Grosse, Philipp, Museteanu, Crisan, Utermöhlen, Olaf, Pircher, Hanspeter, von Weizsäcker, Fritz, Wallich, Reinhard, Müllbacher, Arno, Simon, Markus M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2001
Ábhair:
Pathogenesis and Immunity
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC115123/
https://ncbi.nlm.nih.gov/pubmed/11507223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8781-8791.2001
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