Concerted Action of the FasL/Fas and Perforin/Granzyme A and B Pathways Is Mandatory for the Development of Early Viral Hepatitis but Not for Recovery from Viral Infection

Cytotoxic T lymphocytes (CTL) play a major role in the recovery from primary viral infections and the accompanying tissue injuries. However, it is unclear to what extent the two main cytolytic pathways, perforin-granzyme A and B exocytosis and Fas ligand (FasL)-Fas interaction, contribute to these p...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Balkow, Sandra, Kersten, Astrid, Tran, Thi Thanh Thao, Stehle, Thomas, Grosse, Philipp, Museteanu, Crisan, Utermöhlen, Olaf, Pircher, Hanspeter, von Weizsäcker, Fritz, Wallich, Reinhard, Müllbacher, Arno, Simon, Markus M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11507223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.18.8781-8791.2001
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