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Lack of both Fas Ligand and Perforin Protects from Flavivirus-Mediated Encephalitis in Mice

The mechanism by which encephalitic flaviviruses enter the brain to inflict a life-threatening encephalomyelitis in a small percentage of infected individuals is obscure. We investigated this issue in a mouse model for flavivirus encephalitis in which the virus was administered to 6-week-old animals...

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Vydáno v:J Virol
Hlavní autoři: Licon Luna, Rosa M., Lee, Eva, Müllbacher, Arno, Blanden, Robert V., Langman, Rod, Lobigs, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884544/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3202-3211.2002
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