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Lack of both Fas Ligand and Perforin Protects from Flavivirus-Mediated Encephalitis in Mice

The mechanism by which encephalitic flaviviruses enter the brain to inflict a life-threatening encephalomyelitis in a small percentage of infected individuals is obscure. We investigated this issue in a mouse model for flavivirus encephalitis in which the virus was administered to 6-week-old animals...

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Detalhes bibliográficos
Main Authors: Licon Luna, Rosa M., Lee, Eva, Müllbacher, Arno, Blanden, Robert V., Langman, Rod, Lobigs, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136025/
https://ncbi.nlm.nih.gov/pubmed/11884544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3202-3211.2002
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