Theiler’s Virus Infection of Perforin-Deficient Mice

Theiler’s virus, a murine picornavirus, infects the central nervous systems of C57BL/6 mice and is cleared after approximately 10 days by a process which requires CD8(+) cytotoxic T cells. We used perforin-deficient C57BL/6 mice to test the role of this protein in viral clearance. Perforin-deficient...

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Bibliographic Details
Main Authors: Pena Rossi, Claudia, McAllister, Andrés, Tanguy, Myriam, Kägi, David, Brahic, Michel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109696/
https://ncbi.nlm.nih.gov/pubmed/9557751
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