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Proteasomal degradation restricts the nuclear lifespan of AID
Activation-induced cytidine deaminase (AID) initiates all postrearrangement processes that diversify the immunoglobulin repertoire by specific deamination of cytidines at the immunoglobulin (Ig) locus. As uncontrolled expression of AID is potentially mutagenic, different types of regulation, particu...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413033/ https://ncbi.nlm.nih.gov/pubmed/18474627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070950 |
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