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Competitive repair pathways in immunoglobulin gene hypermutation
This review focuses on the contribution of translesion DNA polymerases to immunoglobulin gene hypermutation, in particular on the roles of DNA polymerase eta (Polη) in the generation of mutations at A/T bases from the initial cytosine-targeted activation-induced cytidine deaminase (AID)-mediated dea...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Royal Society
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660922/ https://ncbi.nlm.nih.gov/pubmed/19010770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0206 |
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