Competitive repair pathways in immunoglobulin gene hypermutation

This review focuses on the contribution of translesion DNA polymerases to immunoglobulin gene hypermutation, in particular on the roles of DNA polymerase eta (Polη) in the generation of mutations at A/T bases from the initial cytosine-targeted activation-induced cytidine deaminase (AID)-mediated dea...

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Detalhes bibliográficos
Main Authors: Reynaud, Claude-Agnès, Delbos, Frédéric, Faili, Ahmad, Guéranger, Quentin, Aoufouchi, Said, Weill, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2008
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660922/
https://ncbi.nlm.nih.gov/pubmed/19010770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0206
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