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Antiangiogenic activity of aplidine, a new agent of marine origin

The antineoplastic compound aplidine, a new marine-derived depsipeptide, has shown preclinical activity in vitro on haematological and solid tumour cell lines. It is currently in early phase clinical trials. The exact mechanism of action of this anticancer agent still needs to be clarified. We have...

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Autores principales: Taraboletti, G, Poli, M, Dossi, R, Manenti, L, Borsotti, P, Faircloth, G T, Broggini, M, D'Incalci, M, Ribatti, D, Giavazzi, R
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409535/
https://ncbi.nlm.nih.gov/pubmed/15173857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601864
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