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Antiangiogenic activity of aplidine, a new agent of marine origin

The antineoplastic compound aplidine, a new marine-derived depsipeptide, has shown preclinical activity in vitro on haematological and solid tumour cell lines. It is currently in early phase clinical trials. The exact mechanism of action of this anticancer agent still needs to be clarified. We have...

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Bibliografske podrobnosti
Main Authors: Taraboletti, G, Poli, M, Dossi, R, Manenti, L, Borsotti, P, Faircloth, G T, Broggini, M, D'Incalci, M, Ribatti, D, Giavazzi, R
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409535/
https://ncbi.nlm.nih.gov/pubmed/15173857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601864
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