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Establishment and characterisation of a human carcinoma cell line with acquired resistance to Aplidin™

Aplidin™ (APL) is a new antitumoral drug from marine origin currently in phase II clinical trials against a wide multiplicity of cancers. As resistance may be, as with other drugs, an important obstacle to the APL therapeutic efficacy, we have established an acquired resistance cellular model by con...

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Bibliographic Details
Main Authors: Losada, A, López-Oliva, J M, Sánchez-Puelles, J M, García-Fernández, L F
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409906/
https://ncbi.nlm.nih.gov/pubmed/15365569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602166
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