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Antitumour and antiangiogenic effects of Aplidin® in the 5TMM syngeneic models of multiple myeloma

Aplidin® is an antitumour drug, currently undergoing phase II evaluation in different haematological and solid tumours. In this study, we analysed the antimyeloma effects of Aplidin in the syngeneic 5T33MM model, which is representable for the human disease. In vitro, Aplidin inhibited 5T33MMvv DNA...

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Détails bibliographiques
Auteurs principaux: Caers, J, Menu, E, De Raeve, H, Lepage, D, Van Valckenborgh, E, Van Camp, B, Alvarez, E, Vanderkerken, K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441967/
https://ncbi.nlm.nih.gov/pubmed/18521088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604388
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