Specific roles for the PI3K and the MEK–ERK pathway in IGF-1-stimulated chemotaxis, VEGF secretion and proliferation of multiple myeloma cells: study in the 5T33MM model

Insulin-like growth factor-1 (IGF-1) has been described as an important factor in proliferation, cell survival and migration of multiple myeloma (MM) cells. Angiogenesis correlates with development and prognosis of the MM disease. Vascular endothelial growth factor (VEGF) is one of the prominent fac...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Menu, E, Kooijman, R, Valckenborgh, E Van, Asosingh, K, Bakkus, M, Camp, B Van, Vanderkerken, K
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2004
נושאים:
Experimental Therapeutics
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409634/
https://ncbi.nlm.nih.gov/pubmed/14997210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601613
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