Cell cycle phase perturbations and apoptosis in tumour cells induced by aplidine

Aplidine, dehydrodidemnin B, is a marine depsipeptide isolated from the Mediterranean tunicate Aplidium albicans currently in phase II clinical trial. In human Molt-4 leukaemia cells Aplidine was found to be cytotoxic at nanomolar concentrations and to induce both a G(1) arrest and a G(2) blockade....

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Erba, E, Bassano, L, Di Liberti, G, Muradore, I, Chiorino, G, Ubezio, P, Vignati, S, Codegoni, A, Desiderio, M A, Faircloth, G, Jimeno, J, D'Incalci, M
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2002
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375382/
https://ncbi.nlm.nih.gov/pubmed/11986788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600265
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы