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Dynamics of cell cycle phase perturbations by trabectedin (ET‐743) in nucleotide excision repair (NER)‐deficient and NER‐proficient cells, unravelled by a novel mathematical simulation approach
Abstract. Objectives: Trabectedin (ET‐743, Yondelis(®)) is a natural marine product, with antitumour activity, currently in phase II/III clinical trials. Previous studies have shown that cells hypersensitive to ultraviolet (UV)‐rays because of nucleotide excision repair (NER) deficiency, were resis...
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| Publicado no: | Cell Prolif |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6760722/ https://ncbi.nlm.nih.gov/pubmed/18021177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2007.00469.x |
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