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Trabectedin and Plitidepsin: Drugs from the Sea that Strike the Tumor Microenvironment

The prevailing paradigm states that cancer cells acquire multiple genetic mutations in oncogenes or tumor suppressor genes whose respective activation/up-regulation or loss of function serve to impart aberrant properties, such as hyperproliferation or inhibition of cell death. However, a tumor is no...

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Bibliografiske detaljer
Main Authors: Galmarini, Carlos M., D’Incalci, Maurizio, Allavena, Paola
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944511/
https://ncbi.nlm.nih.gov/pubmed/24473171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12020719
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