Cell cycle perturbations and apoptosis induced by isohomohalichondrin B (IHB), a natural marine compound

Isohomohalichondrin B (IHB), a novel marine compound with anti-tumoral activity, extracted from the Lissodendorix sponge, inhibits GTP binding to tubulin, preventing microtubule assembly. Cell cycle perturbations and apoptosis induced by IHB were investigated on selected human cancer cell lines by u...

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Bibliographic Details
Main Authors: Bergamaschi, D, Ronzoni, S, Taverna, S, Faretta, M, Feudis, P De, Faircloth, G, Jimeno, J, Erba, E, D'Incalci, M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1999
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362206/
https://ncbi.nlm.nih.gov/pubmed/9888468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690044
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