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Molecular Characterization of V59E NIS, a Na(+)/I(−) Symporter Mutant that Causes Congenital I(−) Transport Defect
I(−) is actively transported into thyrocytes via the Na(+)/I(−) symporter (NIS), a key glycoprotein located on the basolateral plasma membrane. The cDNA encoding rat NIS was identified in our laboratory, where an extensive structure/function characterization of NIS is being conducted. Several NIS mu...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Endocrine Society
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2408800/ https://ncbi.nlm.nih.gov/pubmed/18339708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0027 |
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