Á lódáil...
The iodide-transport-defect-causing mutation R124H: a δ-amino group at position 124 is critical for maturation and trafficking of the Na(+)/I(−) symporter
Na(+)/I(−) symporter (NIS)-mediated active accumulation of I(−) in thyrocytes is a key step in the biosynthesis of the iodine-containing thyroid hormones T(3) and T(4). Several NIS mutants have been identified as a cause of congenital I(−) transport defect (ITD), and their investigation has yielded...
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Main Authors: | , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
The Company of Biologists
2013
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3730242/ https://ncbi.nlm.nih.gov/pubmed/23690546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.120246 |
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