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Molecular Characterization of V59E NIS, a Na(+)/I(−) Symporter Mutant that Causes Congenital I(−) Transport Defect

I(−) is actively transported into thyrocytes via the Na(+)/I(−) symporter (NIS), a key glycoprotein located on the basolateral plasma membrane. The cDNA encoding rat NIS was identified in our laboratory, where an extensive structure/function characterization of NIS is being conducted. Several NIS mu...

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Detalhes bibliográficos
Main Authors: Reed-Tsur, Mia D., De la Vieja, Antonio, Ginter, Christopher S., Carrasco, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408800/
https://ncbi.nlm.nih.gov/pubmed/18339708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0027
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