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The Na(+)/I(−) symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate

The Na(+)/I(−) symporter (NIS) is a key plasma membrane protein that mediates active I(−) uptake in the thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na(+) per I(−). In the thyroid, NIS-mediated I(−) uptake is the first step in the biosynthesis of the iodine-co...

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Detalhes bibliográficos
Main Authors: Dohán, Orsolya, Portulano, Carla, Basquin, Cécile, Reyna-Neyra, Andrea, Amzel, L. Mario, Carrasco, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154417/
https://ncbi.nlm.nih.gov/pubmed/18077370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707207104
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