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The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications
Active iodide (I(−)) transport in both the thyroid and some extrathyroidal tissues is mediated by the N a(+)/I(−) symporter (NIS). In the thyroid, NIS-mediated I(−) uptake plays a pivotal role in thyroid hormone (TH) biosynthesis. THs are key during embryonic and postembryonic development and critic...
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| Gepubliceerd in: | Annu Rev Physiol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5739519/ https://ncbi.nlm.nih.gov/pubmed/28192058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-022516-034125 |
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