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The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications

Active iodide (I(−)) transport in both the thyroid and some extrathyroidal tissues is mediated by the N a(+)/I(−) symporter (NIS). In the thyroid, NIS-mediated I(−) uptake plays a pivotal role in thyroid hormone (TH) biosynthesis. THs are key during embryonic and postembryonic development and critic...

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Bibliografische gegevens
Gepubliceerd in:Annu Rev Physiol
Hoofdauteurs: Ravera, Silvia, Reyna-Neyra, Andrea, Ferrandino, Giuseppe, Amzel, L. Mario, Carrasco, Nancy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739519/
https://ncbi.nlm.nih.gov/pubmed/28192058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-022516-034125
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