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Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity

BACKGROUND: Sodium/iodide symporter (NIS) mediates the active transport and accumulation of iodide from the blood into the thyroid gland. His-226 located in the extracellular region of NIS has been demonstrated to be critical for iodide transport in our previous study. The conserved charged amino ac...

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Detalhes bibliográficos
Main Authors: Li, Chia-Cheng, Ho, Tin-Yun, Kao, Chia-Hung, Wu, Shih-Lu, Liang, Ji-An, Hsiang, Chien-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002920/
https://ncbi.nlm.nih.gov/pubmed/21092238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-17-89
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