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Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age

Cytokines and inflammation have been implicated in the pathogenesis of heart failure. For example, IL-6 family cytokines and the gp130 receptor play important roles in cardiac myocyte survival and hypertrophy. Signal transducer and activator of transcription 3 (STAT3) is a major signaling protein th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jacoby, Jörg J., Kalinowski, April, Liu, Mu-Gen, Zhang, Samuel S.-M., Gao, Qian, Chai, Gui-Xuan, Ji, Lan, Iwamoto, Yoshiki, Li, En, Schneider, Michael, Russell, Kerry S., Fu, Xin-Yuan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC240721/
https://ncbi.nlm.nih.gov/pubmed/14566054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2134694100
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