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Megamitochondria in cardiomyocytes of a knockout (Klf15−/−) mouse

The Kruppel-like Factors (KLF) family of zinc-finger transcriptional regulators control many aspects of cardiomyocyte structure and function. Deletion of Klf15 from the nuclear genome in mice affects cardiac mitochondria. Some become grossly enlarged, extending many sarcomeres in length. These displ...

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Detalhes bibliográficos
Publicado no:Ultrastruct Pathol
Main Authors: Tandler, Bernard, Fujioka, Hisashi, Hoppel, Charles L., Haldar, Saptarsi M., Jain, Mukesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827860/
https://ncbi.nlm.nih.gov/pubmed/26111268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01913123.2015.1042610
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