Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age

Cytokines and inflammation have been implicated in the pathogenesis of heart failure. For example, IL-6 family cytokines and the gp130 receptor play important roles in cardiac myocyte survival and hypertrophy. Signal transducer and activator of transcription 3 (STAT3) is a major signaling protein th...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Jacoby, Jörg J., Kalinowski, April, Liu, Mu-Gen, Zhang, Samuel S.-M., Gao, Qian, Chai, Gui-Xuan, Ji, Lan, Iwamoto, Yoshiki, Li, En, Schneider, Michael, Russell, Kerry S., Fu, Xin-Yuan
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC240721/
https://ncbi.nlm.nih.gov/pubmed/14566054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2134694100
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker