Učitavanje...
Normal host prion protein (PrP(C)) is required for scrapie spread within the central nervous system
Mice devoid of PrP(C) (Prnp(o/o)) are resistant to scrapie and do not allow propagation of the infectious agent (prion). PrP(C)-expressing neuroectodermal tissue grafted into Prnp(o/o) brains but not the surrounding tissue consistently exhibits scrapie-specific pathology and allows prion replication...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences of the USA
1996
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24061/ https://ncbi.nlm.nih.gov/pubmed/8917559 |
| Oznake: |
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