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IL-2 and IL-21 confer opposing differentiation programs to CD8(+) T cells for adoptive immunotherapy
IL-2 and IL-21 are closely related cytokines that might have arisen by gene duplication. Both cytokines promote the function of effector CD8(+) T cells, but their distinct effects on antigen-driven differentiation of naive CD8(+) T cells into effector CD8(+) T cells are not clearly understood. We fo...
Gorde:
Egile Nagusiak: | , , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society of Hematology
2008
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396726/ https://ncbi.nlm.nih.gov/pubmed/18276844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-113050 |
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