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Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis

Tau is an intrinsically unstructured microtubule (MT)-associated protein capable of binding to and organizing MTs into evenly spaced parallel assemblies known as “MT bundles.” How tau achieves MT bundling is enigmatic because each tau molecule possesses only one MT-binding region. To dissect this co...

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Bibliografische gegevens
Hoofdauteurs: Rosenberg, Kenneth J., Ross, Jennifer L., Feinstein, H. Eric, Feinstein, Stuart C., Israelachvili, Jacob
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396711/
https://ncbi.nlm.nih.gov/pubmed/18495933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802036105
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