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Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration

The neural microtubule-associated protein tau binds to and stabilizes microtubules. Because of alternative mRNA splicing, tau is expressed with either 3 or 4 C-terminal repeats. Two observations indicate that differences between these tau isoforms are functionally important. First, the pattern of ta...

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Detalhes bibliográficos
Main Authors: Bunker, Janis M., Wilson, Leslie, Jordan, Mary Ann, Feinstein, Stuart C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC420096/
https://ncbi.nlm.nih.gov/pubmed/15020716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-01-0062
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