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Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration

The neural microtubule-associated protein tau binds to and stabilizes microtubules. Because of alternative mRNA splicing, tau is expressed with either 3 or 4 C-terminal repeats. Two observations indicate that differences between these tau isoforms are functionally important. First, the pattern of ta...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Principais autores: Bunker, Janis M., Wilson, Leslie, Jordan, Mary Ann, Feinstein, Stuart C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15020716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-01-0062
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