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Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis
Tau is an intrinsically unstructured microtubule (MT)-associated protein capable of binding to and organizing MTs into evenly spaced parallel assemblies known as “MT bundles.” How tau achieves MT bundling is enigmatic because each tau molecule possesses only one MT-binding region. To dissect this co...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396711/ https://ncbi.nlm.nih.gov/pubmed/18495933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802036105 |
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