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Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis

Tau is an intrinsically unstructured microtubule (MT)-associated protein capable of binding to and organizing MTs into evenly spaced parallel assemblies known as “MT bundles.” How tau achieves MT bundling is enigmatic because each tau molecule possesses only one MT-binding region. To dissect this co...

詳細記述

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書誌詳細
主要な著者: Rosenberg, Kenneth J., Ross, Jennifer L., Feinstein, H. Eric, Feinstein, Stuart C., Israelachvili, Jacob
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396711/
https://ncbi.nlm.nih.gov/pubmed/18495933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802036105
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