Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment

Tau, an intrinsically disordered protein confined to neuronal axons, binds to and regulates microtubule dynamics. Although there have been observations of string-like microtubule fascicles in the axon initial segment (AIS) and hexagonal bundles in neurite-like processes in non-neuronal cells overexp...

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Vydáno v:Nat Commun
Hlavní autoři: Chung, Peter J., Song, Chaeyeon, Deek, Joanna, Miller, Herbert P., Li, Youli, Choi, Myung Chul, Wilson, Leslie, Feinstein, Stuart C., Safinya, Cyrus R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962469/
https://ncbi.nlm.nih.gov/pubmed/27452526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12278
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