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Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment

Tau, an intrinsically disordered protein confined to neuronal axons, binds to and regulates microtubule dynamics. Although there have been observations of string-like microtubule fascicles in the axon initial segment (AIS) and hexagonal bundles in neurite-like processes in non-neuronal cells overexp...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chung, Peter J., Song, Chaeyeon, Deek, Joanna, Miller, Herbert P., Li, Youli, Choi, Myung Chul, Wilson, Leslie, Feinstein, Stuart C., Safinya, Cyrus R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962469/
https://ncbi.nlm.nih.gov/pubmed/27452526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12278
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