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Oligomerization of the Microtubule Associated Protein Tau is Mediated by its N-Terminal Sequences: Implications for Normal and Pathological Tau Action

Despite extensive structure-function analyses, the molecular mechanisms of normal and pathological tau action remain poorly understood. How does the C-terminal microtubule-binding region regulate microtubule dynamics and bundling? In what biophysical form does tau transfer trans-synaptically from on...

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Dades bibliogràfiques
Publicat a:J Neurochem
Autors principals: Feinstein, H. Eric, Benbow, Sarah J., LaPointe, Nichole E., Patel, Nirav, Ramachandran, Srinivasan, Do, Thanh D., Gaylord, Michelle R., Huskey, Noelle E., Dressler, Nicolette, Korff, Megan, Quon, Brady, Cantrell, Kristi Lazar, Bowers, Michael T., Lal, Ratnesh, Feinstein, Stuart C.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899250/
https://ncbi.nlm.nih.gov/pubmed/26953146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13604
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