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Oligomerization of the Microtubule Associated Protein Tau is Mediated by its N-Terminal Sequences: Implications for Normal and Pathological Tau Action

Despite extensive structure-function analyses, the molecular mechanisms of normal and pathological tau action remain poorly understood. How does the C-terminal microtubule-binding region regulate microtubule dynamics and bundling? In what biophysical form does tau transfer trans-synaptically from on...

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Bibliografski detalji
Izdano u:J Neurochem
Glavni autori: Feinstein, H. Eric, Benbow, Sarah J., LaPointe, Nichole E., Patel, Nirav, Ramachandran, Srinivasan, Do, Thanh D., Gaylord, Michelle R., Huskey, Noelle E., Dressler, Nicolette, Korff, Megan, Quon, Brady, Cantrell, Kristi Lazar, Bowers, Michael T., Lal, Ratnesh, Feinstein, Stuart C.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899250/
https://ncbi.nlm.nih.gov/pubmed/26953146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13604
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