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Direct measurement of metal ion chelation in the active site of human ferrochelatase

The final step in heme biosynthesis, insertion of ferrous iron into protoporphyrin IX, is catalyzed by protoporphyrin IX ferrochelatase (E.C. 4.99.1.1). It is demonstrated that the pre-steady state human ferrochelatase (R115L) shows a stoichiometric burst of product formation and substrate consumpti...

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Bibliografski detalji
Glavni autori: Hoggins, M., Dailey, H.A., Hunter, C.N., Reid, J.D.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396339/
https://ncbi.nlm.nih.gov/pubmed/17566985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi602418e
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