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Substrate interactions with human ferrochelatase

Ferrochelatase, the terminal enzyme in heme biosynthesis, catalyzes the insertion of ferrous iron into protoporphyrin IX to form protoheme IX. Human ferrochelatase is a homodimeric, inner mitochondrial membrane-associated enzyme that possesses an essential [2Fe-2S] cluster. In this work, we report t...

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Detalhes bibliográficos
Main Authors: Medlock, Amy, Swartz, Larkin, Dailey, Tamara A., Dailey, Harry A., Lanzilotta, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794275/
https://ncbi.nlm.nih.gov/pubmed/17261801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606144104
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