Deletion of Ptpn11 (Shp2) in Cardiomyocytes Causes Dilated Cardiomyopathy via Effects on the Erk/MAPK and RhoA Signaling Pathways

BACKGROUND: Heart failure is the leading cause of death in the U.S. By delineating the pathways that regulate cardiomyocyte function, the pathogenesis of cardiac disease can be better understood. Many cardiomyocyte signaling pathways activate protein-tyrosine kinases. However, the role of specific p...

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Detaylı Bibliyografya
Asıl Yazarlar: Kontaridis, Maria I., Yang, Wentian, Bence, Kendra K., Cullen, Darragh, Wang, Bo, Bodyak, Natalya, Ke, Qingen, Hinek, Aleksander, Kang, Peter M., Liao, Ronglih, Neel, Benjamin G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394674/
https://ncbi.nlm.nih.gov/pubmed/18316486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.728865
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