RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis

The Ras-related guanosine triphosphatase RhoA mediates pathological cardiac hypertrophy, but also promotes cell survival and is cardioprotective after ischemia/reperfusion injury. To understand how RhoA mediates these opposing roles in the myocardium, we generated mice with a cardiomyocyte-specific...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Signal
Asıl Yazarlar: Lauriol, Jessica, Keith, Kimberly, Jaffré, Fabrice, Couvillon, Anthony, Saci, Abdel, Goonasekera, Sanjeewa A., McCarthy, Jason R., Kessinger, Chase W., Wang, Jianxun, Ke, Qingen, Kang, Peter M., Molkentin, Jeffery D., Carpenter, Christopher, Kontaridis, Maria I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300109/
https://ncbi.nlm.nih.gov/pubmed/25336613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005262
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller