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The Role of the Protein Tyrosine Phosphatase SHP2 in Cardiac Development and Disease

Congenital heart disease is the most common human developmental disorder, affecting ~1:100 newborns, and is the primary cause of birth-defect related deaths worldwide. As a major regulator of receptor tyrosine kinase (RTK), cytokine and G-protein coupled receptor signaling, the non-receptor protein...

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Detalhes bibliográficos
Publicado no:Semin Cell Dev Biol
Main Authors: Lauriol, Jessica, Jaffre, Fabrice, Kontaridis, Maria I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339543/
https://ncbi.nlm.nih.gov/pubmed/25256404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2014.09.013
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