MATRIX METALLOPROTEINASE-ACTIVATED ANTHRAX LETHAL TOXIN DEMONSTRATES HIGH POTENCY IN TARGETING TUMOR VASCULATURE

Anthrax lethal toxin (LT), a virulence factor secreted by Bacillus anthracis, is selectively toxic to human melanomas with the BRAF V600E activating mutation due to its proteolytic activities toward the mitogen-activated protein kinase kinases (MEKs). To develop LT variants with lower in vivo toxici...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Shihui, Wang, Hailun, Currie, Brooke M., Molinolo, Alfredo, Leung, Howard J., Moayeri, Mahtab, Basile, John R., Alfano, Randall W., Gutkind, J. Silvio, Frankel, Arthur E., Bugge, Thomas H., Leppla, Stephen H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394502/
https://ncbi.nlm.nih.gov/pubmed/17974567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707419200
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak