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Comparative lesion sequencing provides insights into tumor evolution

We show that the times separating the birth of benign, invasive, and metastatic tumor cells can be determined by analysis of the mutations they have in common. When combined with prior clinical observations, these analyses suggest the following general conclusions about colorectal tumorigenesis: (i)...

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書誌詳細
主要な著者: Jones, Siân, Chen, Wei-dong, Parmigiani, Giovanni, Diehl, Frank, Beerenwinkel, Niko, Antal, Tibor, Traulsen, Arne, Nowak, Martin A., Siegel, Christopher, Velculescu, Victor E., Kinzler, Kenneth W., Vogelstein, Bert, Willis, Joseph, Markowitz, Sanford D.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393770/
https://ncbi.nlm.nih.gov/pubmed/18337506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712345105
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