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Comparative lesion sequencing provides insights into tumor evolution
We show that the times separating the birth of benign, invasive, and metastatic tumor cells can be determined by analysis of the mutations they have in common. When combined with prior clinical observations, these analyses suggest the following general conclusions about colorectal tumorigenesis: (i)...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2393770/ https://ncbi.nlm.nih.gov/pubmed/18337506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712345105 |
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