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Design and analysis issues in genome-wide somatic mutation studies of cancer

The availability of the human genome sequence and progress in sequencing and bioinformatic technologies have enabled genome-wide investigation of somatic mutations in human cancers. This article briefly reviews challenges arising in the statistical analysis of mutational data of this kind. A first c...

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Hlavní autoři: Parmigiani, Giovanni, Boca, Simina, Lin, Jimmy, Kinzler, Kenneth W., Velculescu, Victor, Vogelstein, Bert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820387/
https://ncbi.nlm.nih.gov/pubmed/18692126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2008.07.005
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