Prevalence of somatic alterations in the colorectal cancer cell genome

Although a small fraction of human cancers have increased rates of somatic mutation because of known deficiencies in DNA repair, little is known about the prevalence of somatic alterations in the vast majority of human cancers. To systematically assess nonsynonymous somatic alterations in colorectal...

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Detalhes bibliográficos
Main Authors: Wang, Tian-Li, Rago, Carlo, Silliman, Natalie, Ptak, Janine, Markowitz, Sanford, Willson, James K. V., Parmigiani, Giovanni, Kinzler, Kenneth W., Vogelstein, Bert, Velculescu, Victor E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122475/
https://ncbi.nlm.nih.gov/pubmed/11867767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261714699
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