Comparative lesion sequencing provides insights into tumor evolution

We show that the times separating the birth of benign, invasive, and metastatic tumor cells can be determined by analysis of the mutations they have in common. When combined with prior clinical observations, these analyses suggest the following general conclusions about colorectal tumorigenesis: (i)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jones, Siân, Chen, Wei-dong, Parmigiani, Giovanni, Diehl, Frank, Beerenwinkel, Niko, Antal, Tibor, Traulsen, Arne, Nowak, Martin A., Siegel, Christopher, Velculescu, Victor E., Kinzler, Kenneth W., Vogelstein, Bert, Willis, Joseph, Markowitz, Sanford D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2008
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393770/
https://ncbi.nlm.nih.gov/pubmed/18337506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712345105
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